Informatie over wetenschappelijk onderzoek door het EPZM

Publicaties

• Publicaties 2013-2026

  2026

  Moyke A.J. Versluis, Froukje E. de Vries, Yvette M. van der Linden, Marianne Kool, Jarmo C.B. Hunting, Hanneke W.M. van Laarhoven, Arnold Baars, Sander M. de Hosson, Wouter de K. Jong, Mathijs P. Hendriks, Marieke H.J. van den Beuken- van Everdingen, Tineke J. Smilde, Magdolen Youssef-El Soud, Marjolein H. Tilkema-Tiebosch, Dirkje Sommeijer, Alexander de Graeff, Caroline Mandigers, Lia van Zuylen, Art Vreugdenhil, Annemieke van der Padt-Pruijsten, Evelien J.M. Kuip, Lobke van Leeuwen-Snoeks, Lonneke V. van de Poll-Franse, Natasja J.H. Raijmakers. Death anxiety during the last year of life in patients with advanced cancer: longitudinal results from the eQuiPe study. Psycho-oncology 2026  (IF 3.5) https://doi.org/10.1002/pon.70429

  Van der Meulen, Annelot; Stoppelenburg, Arianne; Theunissen, Maurice; De Nijs, Ellen; van den Beuken-van Everdingen, Marieke; van der Linden, Yvette. Dry mouth in palliative care: a systematic review of clinical practice guidelines around the world. Palliative Medicine 2026 accepted (IF 3.9)

  Miriam van der Velden, Nick Visschers, Miriam Faes, Bart Spaetgens, Eline Brundel, Marieke van den Beuken-van Everdingen, Arnela Suman. Beyond Pain Relief: A Thematic Exploration of Informal Caregiver Experiences and Needs Following SPING Block Treatment in Geriatric Hip Fracture Patients. European Geriatric Medicine accepted 2026 (IF 3.6) doi.org/10.1007/s41999-026-01432-y

  Annette WG van der Velden, Albert H de Heij, Marieke HJ van den Beuken, Evelien JM Kuip, Ginette M Hesselmann, Ellen JM de Nijs, MR Rosy El Aissati-Caldwell, Astrid W Oosten, Anna KL Reyners, Pauline de Graeff. Identification of patients with a limited life expectancy and the involvement of palliative care teams in Dutch hospitalized patients: a flash mob study. BMC Palliative Care….accepted 2026 (2.5)

  Moyke A.J. Versluis, Yvette M. van der Linden, Lobke van Leeuwen-Snoeks, Marieke H.J. van den Beuken- van Everdingen, Mathijs P. Hendriks, Ben E.E.M. van den Borne, Dirkje Sommeijer, Jean-Paul A. van Basten, Annemieke van der Padt-Pruijsten, Alexander de Graeff, Jarmo C.B. Hunting, Evelien J.M. Kuip, Anne S.R. van Lindert, Maggy Youssef-El Soud, Martine F. Thijs-Visser, Art Vreugdenhil, Hanneke W.M. van Laarhoven, Wouter K. de Jong, Caroline Mandigers, Lia van Zuylen, Jeroen kloover, Tineke J. Smilde, Lonneke V. van de Poll-Franse & Natasja J.H. Raijmakers. Patients’ and relatives’ perspectives on the quality of end-of-Life care in advanced cancer: from the final months to bereavement. PLOS Medicine 2026;feb 9:1-17 (IF 15.8) doi.org/10.1371/journal.pone.0342068
   

  2025

  Morena Shkodra, Amaia Urrizola, Marie Fallon, Per Sjøgren, Marieke van den Beuken-van Everdingen, Katarina Hagen, Marianne Jensen Hjermstad, Tonje Lundeby, Stein Kaasa, Augusto Caraceni on behalf of the MyPath consortium. The MyPath Pain Pathway: developing a digital patient-centred care pathway for cancer pain. JPSM 2025;70(6):592-601 (IF 3.5)

  Maurice Theunissen, Sacha Lardenoye, Marieke H.J. van den Beuken-van Everdingen & Patricia M. Stassen. The surprise question: predictive accuracy in an unselected emergency department population - a prospective study in nurse and physisians. Annals of Medicine 2025, VOL.57, NO 1, 2529575

  Miriam WA van der Velden, Miriam C Faes, Frank PJF de Loos, Niels Berende, Marieke MHJ van den Beuken-van Everdingen, Arnela Suman. “SPING Block Analgesia in Non-Operative Proximal Femur Fracture Management in Frail Older Adults: A Retrospective Cohort Study. Geriatrics 2025;10(1):1-14 (IF 2.1) doi.org/10.3390/geriatrics10010010

  D. Bastings, T. Schermer, C. Tromp, B. Vriens, Dr. T.J Smilde, M.P. Hendriks, J van Roij , Dr. C. Mandigers, Prof. dr. M.H.J. van den Beuken – Everdingen, Dr. D.W. Sommeijer, Prof. Dr. H.W.M. van Laarhoven, Dr. N.J.H., Raijmakers. Supportive care needs in patients with advanced cancer who experience psychological problems, and their associated characteristics: a multicentre observational cohort study (eQuiPe study). J of Palliative Medicine 2025;28(5):571-579 (IF 2.8)

  2024

  Wetenschappelijke publicaties

  Andrew Davies, Norah Fagan, Jenny Power and Amy Taylor met medewerking van o.a. Marieke H.J. van den Beuken. ‘Constipation’: One word, many meanings amongst persons with cancer: An observational study.

  Maike S Imkamp, Maurice Theunissen, Sander M van Kuijk, Johan Haumann, Oscar Corli, Cristina Bosetti, Wojciech Leppert , Cinzia Brunelli, Ernesto Zecca, Marieke H van den Beuken-van Everdingen . Finding predictors for successful opioid response in cancer patients: An analysis of data from four randomized controlled trials. Pain Practice 2024;24:101-108.

  Julia MM Deuss, Mandy MM Jansen, Monique CT Bongaerts, Maurice Theunissen and Marieke HJ van den Beuken-van Everdingen. A Retrospective Longitudinal Cohort Study: The Effect of Long-Term Use of Methadone and Associated Factors on QTc in a Maintenance Program. Clinmed DOI: 10.23937/2474-3631/1510038
  
  Jeroen R J H Gruiskens, Liesbeth F M van Hoef, Maurice M Theunissen, Annemie M Courtens, Annerika H M Gidding-Slok, Onno C P van Schayck, Marieke M H J van den Beuken-van Everdingen . Recommadations for Improving Chronic Care in Times of a Pandemic Based on Patient Experiences. J Am Med Dir Assoc. 2024 Apr;25(4):623-632.e5.doi: 10.1016/j.jamda.2023.10.013. Epub 2023 Nov 22.

  Maike S.V. Imkamp BSc a c, Maurice Theunissen PhD a, Wolfgang Viechtbauer PhD b, Sander M.J. van Kuijk PhD c, Marieke H.J. van den Beuken – van Everdingen MD, PhD a. Shifting Views on Cancer Pain Management: A Systematic Review and Network Meta-Analysis. JPSM, 4 juni 2024. https://doi.org/10.1016/j.jpainsymman.2024.05.022

  Daniël C.M. Huijten, Laura Hofstede, Sami O. Simons, Stephanie C.M. Ament, Nicolette Gunnink-Boonstra, Marieke H.J. van den Beuken-van Everdingen, Daisy J.A. Janssen. Development of the conversation tool “I-HARP for COPD” for early identification of palliative care needs in patients with chronic obstructive pulmonary disease. Published online by Cambridge University Press:  16 February 2024

  Chantal F R Pereira, Anne-Floor Q Dijxhoorn, Berdine Koekoek, Monique van den Broek, Karin van der Steen, Marijanne Engel, Marjon van Rijn, Judith M Meijers, Jeroen Hasselaar, Agnes van der Heide, Bregje D Onwuteaka-Philipsen, Marieke H J van den Beuken-van Everdingen, Yvette M van der Linden, Manon S Boddaert, Patrick P T Jeurissen, Matthias A W Merkx, Natasja J H Raijmakers. Potentially inappropriate end of life care and healthcare costs in the last 30 days of life in regions providing integrated palliative care in the Netherlands: a registration-based study. International Journal of Integrated Care DOI: 10.5334/ijic.7504

  Wisanne M. Bakker, Maurice Theunissen, Elife Öztürk, Elisabeth Litjens, Annemie Courtens, Marieke HJ van den Beuken- van Everdingen , Marc H Hemmelder. Educational level and gender are associated with emotional well-being in a cohort of Dutch dialysis patients. BMC Nephrology  (2024) 25:179   

  Rapportage 

  Franca Warmenhoven. Pilot Project: Proactieve zorg en zorg voor zingeving voor kwetsbare ouderen in huisartsenpraktijken Maastricht/Heuvelland

  2023

  Rolf A.H. Snijders, Linda Brom, Maurice Theunissen, Marieke H.J. van den Beuken-van Everdingen. Update on Prevalence of Pain in Patients With Cancer a Systematic Literature Review and Meta-Analysis.
  Cancers 2023, 15(3), 591; https://doi.org/10.3390/cancers15030591

  Jeroen R.J.H. Gruiskens, Liesbeth van Hoef, Maurice Theunissen, Annemie M. Courtens, Marieke M.H.J. van den Beuken – van Everdingen, Annerika H.M. Gidding-Slok, Onno C.P. van Schayck. The psychosocial impact of the COVID-19 pandemic on chronic care patients.  DOI:10.1016/j.jamda.2023.01.003

  Posters
  E-StOIC study: single question versus Rome IV diagnostic criteria for diagnosis of opioid-induced constipation
  Prof Andrew Davies, Dr Wendy Oldenmenger, Prof Marieke van den Beuken –van Everdingen, Dr Craig Gouldthorpe1, Norah Fagan

  E-StOIC study: prescribed and non-prescribed management of OIC
  Prof Andrew Davies, Dr Wendy Oldenmenger, Prof Marieke van den Beuken –van Everdingen, Dr Craig Gouldthorpe1, Norah Fagan

  2022

  Verberkt Cornelia, van den Beuken-van Everdingen Marieke, Schols Jos, Wouters Emiel, Janssen Daisy. Morphine for chronic breathlessness in COPD: improvement predictors—cross-sectional study. BMJ Supportive and Palliative Care 2022 doi.org/ 10. 1136/ spcare- 2022-003693) (IF 3.568)

  S. Lardenoye, M. Theunissen, A. N.A. van der Horst-Schrivers, M.H.J. van den Beuken-van Everdingen. A missed opportunity in the ED: Palliative care. American Journal of Emergency Medicine 2022;58:345-346  doi.org/10.1016/j.ajem.2022.04.014  (IF 2.469)

  Y. Oelen, S. Revenberg, J. de Vos-Geelen, R. van Geel, J. Schoenmaekers,  M. van den Beuken-Everdingen, L.B.J. Valkenburg-van Iersel. Cannabinoid consumption among cancer patients receiving systemic anti-cancer treatment in the Netherlands. J Cancer Research and Clinical Oncology 2022;31(5): https://doi.org/10.1007/s00432-022-04085-z (IF 4.553)

  H.H. Stoorvogel, J.C.M. van Haastregt, M. Theunissen, J.J.A.O. Schoenmaekers, A. Hoeben, M.H.J. van den Beuken-van Everdingen. Unacceptable pain in oncology: the patients’ perspective on reasons for absence of pain interventions. European Journal of Cancer Care 2022;31(5):e13628 http://doi.org/10.1111/ecc.13628  (IF 2.520) 

  Maurice Theunissen, Fabienne Magdelijns, Daisy J.A. Janssen, Myrthe W. Naaktgeboren, Annemie Courtens, Sander MJ van Kuijk, Marieke van den Beuken-van Everdingen. The Surprise Question in older hospitalized patients; to use or not to use? JAMDA 2022;23(5):894–896 (IF 4.669) doi.org/10.1016/j.jamda.2022.01.058

  Annelieke Damen, Natasja J.H. Raijmakers, Janneke van Roij, Anja Visser, Marieke van den Beuken-Everdingen, Eveline Kuip, Hanneke W.M. van Laarhoven, Lobke van Leeuwen-Snoeks, Annemieke van der Padt-Pruijsten, Carmen Schuhmann, Tineke J. Smilde, Carlo Leget, George Fitchett. Spiritual well-being and associated factors in Dutch patients with advanced cancer. J Pain Sympt Manage 2022 Mar;63(3):404-414 (IF 3.077)

  Janneke van Roij, Natasja Raijmakers, Laurien Ham, Marieke van den Beuken-van Everdingen et all. Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: a multicenter observational cohort study (eQuiPe) . European Journal of Cancer 2022;165:125-135 (IF 9.162) doi.org/10.1016/j.ejca.2022.01.039

  Andrew Davies, Saverio Cinieri, Denis Dupoiron, Sofia España Fernandez, Johan Leclerc, Vincenzo Montesarchio, Kyriaki Mystakidou, Judith Serna, Jan Tack, on behalf of the NACASY Study Group. A Prospective, Real-World, Multinational Study of Naloxegol for Patients with Cancer Pain Diagnosed with Opioid-Induced Constipation—The NACASY Study. Cancers 2022;14(5):1128 (IF 6.639) doi.org/10.3390/cancers14051128

  Stephanie MC Ament, Lisette M van den Broek, Marieke HJ van den Beuken-van Everdingen, Josiane JJ Boyne, José MC Maessen, Bas C Bekkers, Louise Bellersen, Hans-Peter Brunner-La Rocca, Yvonne Engels,  Daisy JA Janssen. What to consider when implementing a tool for timely recognition of palliative care needs in heart failure: a context-based qualitative study. BMC Palliative Care 2022;21:1-9  doi.org/10.1186/s12904-021-00896-y (IF 2.93)

  Posters

  Maurice Theunissen, Fabienne Magdelijns, Daisy J.A. Janssen, Myrthe W. Naaktgeboren, Annemie Courtens, Sander MJ van Kuijk, Marieke van den Beuken-van Everdingen. The Surprise Question in older hospitalized patients; to use or not to use? 12th World Congress of the EAPC 18 -20 May 2022

  M. H. van den Beuken-van Everdingen1, S. van Kuijk, M. Theunissen, M. Imkamp, J. Haumann, C. Brunelli, W. Leppert, C. Bosetti, O. Corli. Effectivity of 5 different strong opioids in the treatment of pain in oncology. 12th World Congress of the EAPC 18 -20 May 2022

  Maurice Theunissen, Fabienne J.H. Magdelijns, Daisy J.A. Janssen, Myrthe W. Naaktgeboren, Annemie Courtens, Sander M.J. van Kuijk, Marieke van den Beuken-van Everdingen. The Surprise Question in older hospitalized patients; to use or not to use? Dutch-Flemish palliative research days 31 March- 1 April 2022

  M. Imkamp, M. Theunissen, S.M.J. van Kuijk, J. Haumann, M.H.J. van den Beuken - van Everdingen. Effectiviteit van 5 verschillende opioïden voor de behandeling van oncologische pijn: een predictiemodel op basis van geaggregeerde data. Dutch-Flemish palliative research days 31 March- 1 April 2022

  B.D.C. Pouwels, S.O. Simons, M. Theunissen, M.L. Peters, J.J.A.O. Schoenmaekers, S.C.A.M. Bekkers, M.H.J. van den Beuken-van Everdingen. Health care use during COVID-19 and the effect on psychological distress in patients with chronic cardiopulmonary disorders in the Netherlands. Dutch-Flemish palliative research days 31 March- 1 April 2022

  2021

  Aniek Anna Julia Martine Willems MSc, Aliaksandr Fedorovich Kudrashou MD, PhD, Maurice Theunissen PhD, Ann Hoeben MD, PhD, Marieke Henrica Johanna Van den Beuken – Van
  Everdingen MD, PhD. Measuring pain in oncology outpatients: Numeric Rating Scale versus acceptable/non acceptable pain. A prospective single center study.

  Cost-effectiveness of sustained-release morphine for refractory breathlessness in COPD: A randomized clinical trial. Cornelia A. Verberkt a, Marieke H.J. van den Beuken-van Everdingen, Carmen D. Dirksen, Jos M.G.A. Schols, Emiel F.M. Wouters, Daisy J.A. Janssen. Respiratory Medicine 179 (2021) 106330.

  B.D.C. Pouwels, S.O. Simons, M. Theunissen, M.L. Peters, J.J. Schoenmaekers, S.C. Bekkers, M.H.J. van den Beuken-van Everdingen. Healthcare use during COVID-19 and the effect on psychological distress in patients with chronic cardiopulmonary disorders in the Netherlands: a cross- sectional study. BMJ Open 2021;11:e046883.

  Annemieke Wagemans, Willemjan Slort. Palliatieve zorg bij mensen met een verstandelijke beperking. Huisarts en Wetenschap, maart 2021.

  Hille Voss, Anique G.F.M. Vogel, Annemieke M.A. Wagemans, Anneke L. Francke,
  Job F.M. Metsemakers, Annemie M. Courtens, and Anke J.E. de Veer. Development, Implementation, and Evaluation of an Advance Care Planning Program for Professionals in Palliative Care of People With Intellectual Disability. Intellectual and developmental disabilities (AAIDD), 2021, Vol. 59, No. 1, 39–54

  2020

  Stephanie Ament, post-doc onderzoeker en Josiane Boyne, onderzoeker, Maastricht Universitair Medisch Centrum (MUMC+), Daisy Janssen, specialist ouderengeneeskunde en kaderarts palliatieve zorg, Ciro Horn en Universiteit Maastricht, Nicole Uszko-Lencer, cardiologe, MUMC+, Ciro Horn. Tijdig signaleren van palliatieve zorgbehoeften bij gevorderd hartfalen. De ontwikkeling van een hulpmiddel voor zorgverleners. Cordiaal 5-2020

  Maurice Theunissen, PhD, Shanly Rideaux-Seferina, MD, PhD, Fabienne J. Magdelijns, MD, PhD, Daisy J.A. Janssen, MD, PhD, Marieke H.J. van den Beuken-van Everdingen, MD, PhD. Local Oral Pilocarpine Drops for Relieving Xerostomia (Dry Mouth) in elderly: A Pilot Study August 12, 2020DOI:https://doi.org/10.1016/j. jamda.2020.06.036 

  Cornelia A. Verberkt, MSc; Marieke H. J. van den Beuken-van Everdingen, MD, PhD; Jos M. G. A. Schols, MD, PhD; Niels Hameleers, MSc; Emiel F. M.Wouters, MD, PhD; Daisy J. A. Janssen, MD, PhD. Effect of Sustained-Release Morphine for Refractory Breathlessness in Chronic Obstructive Pulmonary Disease on Health Status, A Randomized Clinical Trial. JAMA Internal Medicine. Published online August 17, 2020

  A. de Graeff, M.H.J. van den Beuken-van Everdingen, M.J.M.M Giezeman†, H. Klaren, B. Kramp, M. Martens, M. J. Oortman, P. Oosterhof, A.K.L. Reyners, M. Schielke, M.C. Sieders, M.F.M. Wagemans, M. Gilsing, I. van Trigt. Modulaire revisie van de richtlijn ‘Diagnostiek en behandeling van pijn bij patiënten  met kanker’ (Modular revision of the guideline ‘Diagnostics and treatment of pain in patients with cancer’). Nederlands tijdschrift voor Oncologie 2020;17(2)

  Twee nieuwe richtlijnen. Pijn bij kanker en bij COPD/ hartfalen. Werkgroepleden: Dr. A. de Graeff, drs. L. Bellersen, prof.dr. M.H.J. van den Beuken-van Everdingen, dr. M.J.M.M Giezeman†, drs. H.M. Klaren-Florijn, drs. S.M. de Hosson, B. Kramp, drs. M.J.M. Martens, drs. M.J. Oortman, drs. P. Oosterhof, prof.dr. A.K.L. Reyners, M.A.S. Schielke, drs. M.C. Sieders, dr. M.F.M. Wagemans, drs. M.G. Gilsing en drs. I. van Trigt. Pallium 17 apr. 2020.

  Janssen Daisy JA, Stephanie MC Ament, Josiane Boyne, Jos MGA Schols, Hans-Peter Brunner-La Rocca, Jose MC Maessen, Marieke HJ van den Beuken-van Everdingen. Characteristics for a tool for timely identification of palliative needs in heart failure: The views of Dutch patients, their families and healthcare professionals.  European Journal of Cardiovascular Nursing 0(0) 1-10.

  Courtens Annemie,  Giel Vaessen, Annette Bour. Palliatieve zorg in het onderwijs. TVZ 02/20

  Voss Hille, Anique Vogel, Annemieke M. A. Wagemans, Anneke L. Francke, Job F. M. Metsemakers, Annemie M. Courtens, Anke J. E. de Veer. What is important for advance care planning in the palliative phase of people with intellectual disabilities? A multiperspective interview study. J Appl Res Intellect Disabil. 2020;33:160-171

  2019

  Johan Haumann, MD, Sander M.J. van Kuijk, PhD, Elbert A. Joosten, PhD, and Marieke H.J. van den Beuken-van Everdingen, MD, PhD. The Association between Patient Characteristics and Opioid Treatment Response in Neuropathic and Nociceptive Pain due to Cancer.

  Beuken-van Everdingen MHJ van den, M.A.E. de van der Schueren. Nutrition and Palliative Care Chapter: What about food when there are no more therapeutic options for the bladder cancer? In: Diet and fighting bladder cancer, Maurice Zeegers 2019

  Boer-Beskers Liesbeth de,  dialyseverpleegkundige. M.m.v. dr. E. Litjens, internist-nefroloog; Patricia Savelberg, dialyseverpleegkundige; Sonja Mulder, dialyseverpleegkundige; Marion Simons-de Haas, dialyseverpleegkundige; Anouk Geurts, dialyseverpleegkundige; Joke Leone-Jacobs, dialyseverpleegkundige; Paul Oyen, consulent palliatieve zorg; dr. A. Courtens, coördinator Expertisecentrum palliatieve zorg. Allen werkzaam in het MUMC+. Palliatieve zorg op de afdeling dialyse van het MUMC+. Dialyse & Nefrologie magazine (mag#3_2019_14-17)

  Courtens A, G. Vaessen, A. Bour, A. van Pol, M. van den Beuken–van Everdingen. Basiscompetenties Palliatieve zorg voor verzorgenden en verpleegkundigen. Onderwijs en Gezondheidszorg 2019;4:26-9

  Datla S, Verberkt C.A., Hoye, A., Janssen, D.J.A., and Johnson M.J. Palliat Med. Multi-disciplinary palliative care is effective in people with symptomatic heart failure: a systematic review and narrative synthesis. 2019. 33(8): 1003-16.

  Goërtz Y.M.J., Spruit, M.A., Van ‘t Hul, A.J., Peters, J.B., Van Herck, M., Nakken, N., Djamin, R.S., Burtin, C., Thong, M.S.Y., Coors, A., Meertens-Kerris, Y., Wouters, E.F.M., Prins, J.B., Franssen, F.M.E., Muris, J.W.M., Vanfleteren, L.E.G.W., Sprangers, M.A.G.  Janssen, D.J.A. and Vercoulen, J.H. Fatigue is highly prevalent in patients with COPD and correlates poorly with the degree of airflow limitation. Ther Adv Respir Dis. 2019. 13. 1-13.

  Houben C.H.M., Spruit, M.A., Luyten, H., Pennings, H.-J., van den Boogaart, V.E.M., Creemers, J.P.H.M., Wesseling, G., Wouters, E.F.M., and Janssen, D.J.A. A cluster-randomized trial of a nurse-led advance care planning session in patients with COPD and their loved ones. Thorax. 2019. 74 (4):328-36.

  Janssen, D.J.A., van den Beuken-van Everdingen, M.H.J., Verberkt, C.A., Creemers, J.P.H.M., Wouters, E.F.M. Fentanyl nasal spray in a patient with end-stage COPD and severe chronic breathlessness. Breathe.2019 15 (3) e122-e125.

  Janssen D.J.A., Rechberger, S., Wouters, E.F.M, Schols, J.M.G.A., Johnson, M.J., Currow, D.C., Curtis, J.R. and Spruit, M.A. Clustering of 27,525,663 Death Records from the United States Based on Health Conditions Associated with Death: An Example of big Health Data Exploration. J. Clin. Med. 2019, 8, 922.

  Janssen, D.J.A., Boyne, J., Currow, D.C., Schols, J.M.G.A., Johnson, M.J., Brunner-La Rocca, H.-P. Timely recognition of palliative care needs of patients with advanced chronic heart failure: a pilot study of a Dutch translation of the Needs Assessment Tool: Progressive Disease – Heart Failure (NAT:PD-HF). Eur J Cardiovasc Nurs. 2019. 18(5):375-88.

  Janssen Daisy, Marieke van den Beuken-van Everdingen, Cornelia Verberkt, Jacques Creemers, Emiel Wouters. Excess use of fentanyl nasal spray in a patient with end stage COPD and severe chronic breathlessness: lessons learned. Breathe 2019;15:e122–e125

  Johnson M.J. and Janssen D.J.A. Advance care planning – a “hard” skill for cardiology clinicians? Heart. 2019. 105 (17):1298-99.Klekamp Lisanne M., prof. dr. Marieke H.J. van den Beuken-van Everdingen, dr. Ann Hoeben, dr. Daisy J.A Janssen. Subcutane toediening van levetiracetam ter preventie van insulten in de stervensfase, een case report. Nederlands Vlaams Tijdschrift voor Palliatieve Zorg, 2019;16(2):60-4

  Nakken N., Spruit, M.A., van den Bogaart, E.H.A., Crutzen, R., Muris, J.W., Wouters, E.F.M., Janssen, D.J.A. Identifying causes of perceptual differences in problematic activities of daily life between patients with COPD and proxies: a qualitative study. Aust Occup Ther J. 2019. 66.44-51.

  Pieters Jolien, Diana H.J.M. Dolmans, Daniëlle M.L. Verstegen, Franca Warmenhoven, Annemie M. Courtens, Marieke H.J. van den Beuken-van Everdingen. Palliative care education in the undergraduate medical curricula: Students' views on the importance of, their confidence in, and knowledge of palliative care. BMC Palliative Care 12/2019;18(72))

  Spruit, M.A., Rochester, C.L., Pitta, F., Kenn, K., Schols, A.M.W.J., Hart, N. Wouters, E.F.M., Nava, S., Dreher, M., Janssen, D.J.A., Johnson, M.J., Curtis, J.R., Sastry, M., and Franssen F.M.E. Pulmonary Rehabilitation, Physical Activity, Respiratory Failure, and Palliative Respiratory Care. Thorax. 2019. 74(7):693-99.

  Theunissen Maurice, Mark Martens, Daisy J.A. Janssen, PhD, Jos M.G.A. Schols, PhD, Marieke H.J. van den Beuken-van Everdingen"Premature ending of a medication study in dying patients: lessons learned", research letter. J Pain Sympt Manage 2019;58(5): e4-e7

  Voss, H., A. Vogel, A. M. A. Wagemans, A. L. Francke J. F. M. Metsemakers, A. M. Courtens, A. J. E. deVeer Advance care planning in the palliative phase of people with intellectual disabilities: analysis of medical files and interviews. Journal of Intellectual Disability Research 2019, volume 63 issue 10, 1262-1272

  Voss, H., A. Vogel, A.M.A. Wagemans, A.L. Francke, J.F.M. Metsemakers, A.M. Courtens, A.J.E. de Veer What is important for advance care planning in the palliative phase of people with intellectual disabilities? A multiperspective interview study, Journal of applied research in intellectual disabilities 2020 Mar;33(2):160-171. doi: 10.1111/jar.12653.  Epub 2019 Aug 23

  2018

  Carmen H.M. Houben, Martijn A. Spruit, Hans Luyten, Herman Jan Pennings, Vivian E.M. Van Den Boogaart, Jacques P.H.M. Creemers, Geertjan Wesseling, Emiel F.M. Wouters, Daisy J.A. Janssen. Cluster-randomised trial of a nurse-led advance care planning session in patients with COPD and their loved ones. Thorax. https://doi.org/10.1136/thoraxjnl-2018-211943

  Martens MJM, Janssen DJA, Schols JMGA, Beuken van den - Everdingen van MHJ. Opioid Prescribing Behavior in Long-Term Geriatric Care in the Netherlands. JAMDA. 2018;(11):974-80

  Beuken van den-van Everdingen, M.H.J., van Kuijk, S.M.J., Janssen D.J.A., and Joosten, E.A.J. Treatment of pain in cancer: towards personalised medicine. Cancers. 2018. 10 (12). 10(502) (IF 5.326)

  J. Haumann, S.M.J. van Kuijk, E. A. Joosten, M.H.J. van den Beuken-van Everdingen. The association between patient characteristics and opioid treatment response in neuropathic and nociceptive pain due to cancer. Journal of Palliative Medicine 2018; (IF 2.490)

  Cindy A. Verberkt, Marieke H.J. van den Beuken-van Everdingen, Jos M.G.A. Schols, Sushma Datla, Carmen D. Dirksen, Miriam J. Johnson, Sander M.J. van Kuijk, Emiel F.M. Wouters, Daisy J.A. Janssen. Adverse respiratory effects of opioids for chronic breathlessness: to what extend can we learn lessons from chronic pain? Eur Respir J 2018;52(1):1800882 (IF 12.242) 

  Johan Haumann, Sander M.J. van Kuijk, José W. Geurts, Frank J.P. Hoebers, Bernd Kremer, Elbert A. Joosten, Marieke H.J. van den Beuken-van Everdingen. Methadone versus Fentanyl in Patients with Radiation Induced Nociceptive Pain with Head and Neck Cancer, a randomized controlled non-inferiority trial. Pain Practice 2018;18(3):331-40  (IF 2.495)

  Robert Janknegt, Marieke van den Beuken – van Everdingen, Sjouke Schiere, Michael Überall, Roger Knaggs, Jaquie Hanley, Morten Thronaes. Rapid acting fentanyl formulations in breakthrough pain in cancer. Drug selection by means of the System of Objectified Judgement Analysis. Eur J Hosp Pharm 2018;25:e2 (IF 0.538)

  Vaes, A.W., Delbressine, J.M.L., Mesquita, R., Goertz, Y.M.J., Janssen, D.J.A. Nakken, N., Franssen, F.M.E., Vanfleteren, L.E.G.W., Wouters, E.F.M. and Spruit M.A. The impact of pulmonary rehabilitation on activities of daily living in patients with COPD. J Appl Physiol. 2018. Published online ahead of print.

  Van Herck, M., Spruit, M.A., Burtin, C., Djamin, R., Antons, J., Goertz, Y.M.J., Ebadi, Z., Janssen, D.J.A., Vercoulen, J.H., Peters, J.B., Thong, M.S.Y., Prins, J.B., Otker, J., Coors, A., Sprangers, M.A.G., Muris, J.W.M., Wouters, E.F.M., and van ’t Hul, A. Fatigue is highly prevalent in patients with asthma and contributes to the burden of disease. J Clin Med. 2018. 7(12):471.

  van Beers, M., Janssen, D.J.A., Gosker, H.R., and Schols A.M.W.J. Cognitive impairment in COPD: disease burden, determinants and possible future interventions. Exp Rev Resp Med. 2018. 1-14.

  Houben-Wilke, S., Janssen, D.J.A., Franssen, F.M.E., Vanfleteren, L.E.G.W., Wouters E.F.M., and Spruit, M.A. Contribution of individual COPD Assessment Test (CAT) items to CAT total score and effects of pulmonary rehabilitation on CAT scores. Health Qual Life Outcomes. 2018. 16(1):205.

  Nakken, N., Spruit, M.A., van den Bogaart, E.H.A., Crutzen, R., Muris, J.W., Wouters, E.F.M., Janssen, D.J.A. Identifying causes of perceptual differences in problematic activities of daily life between patients with COPD and proxies: a qualitative study. Aust Occup Ther J. 2018.

  Goërtz, Y.M.J., Looijmans, M.,  Prins, J.B., Janssen, D.J.A., Thong, M.S.Y.,Peters, J.B., Burtin, C., Meertens-Kerris, Y., Coors, A., Muris, J.W.M., Sprangers, M.A.G., Wouters, E.F.M.,  Vercoulen, J.H., and Spruit M.A. Fatigue in patients with Chronic Obstructive Pulmonary Disease: protocol of the longitudinal, observational FAntasTIGUE study. BMJ Open. 2018;8:e021745.

  Janssen, D.J.A., Johnson, M.J., Spruit M.A. Palliative care needs assessment in chronic heart failure. Curr Opin Support Palliat Care. 2018. 12:25-31.

  Jabbarian, L.J., Zwakman M., van der Heide, A., Kars M.C., Janssen, D.J.A., van Delden, J.J.M., Rietjens, J.A.C., Korfage I.J. Advance care planning in chronic respiratory diseases: a systematic review of preferences and practices. Thorax. 2018. 73(3):222-230.

  Cleutjens, F.A.H.M., Spruit, M.A., Ponds, R.W.H.M., Vanfleteren, L.E.G.W., Franssen, F.M.E., Gijsen C., Dijkstra, J.B., Wouters, E.F.M., and Janssen D.J.A. Cognitive impairment and clinical characteristics in patients with COPD. Chron Resp Dis. 2018.15(2):91-102.

  M.P.H. Bischoff, prof. dr. M.H.J. van den Beuken-Everdingen, prof. dr. A-M.C. Dingemans. Effect of early and systematic integration of palliative care in patients with advanced cancer: a randomised controlled trial. van Butsele et all. NTvO 2018;15(6):236-7 Susanto C, Kooman J, Courtens AM, Konings CJAM. Conservative care as a treatment option for patients aged 75 years and older with CKD stage V: a National survey in the Netherlands.Eur Geriatr Med. 2018;9(2):235-242. doi: 10.1007/s41999-018-0031-9. Epub 2018 Feb 12

  2017
  
  Rietjens JAC, Sudore RL, Connolly M, van Delden JJ, Drickamer MA, Droger M, van der Heide A, Heyland DK, Houttekier D, Janssen DJA, Orsi L, Payne S, Seymour J, Jox RJ, Korfage IJ, on behalf of the European Association for Palliative Care. Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care. Lancet Oncol. 2017;18:e543-51

  2016
  J. Haumann, J.W Geurts, S.M.J. van Kuijk, B. Kremer, E.A. Joosten, M.H.J. van den Beuken-van Everdingen. Methadone is superior to fentanyl in treating neuropathic pain in patients with head-and-neck cancer. Eur J Cancer. 2016;65:121-129

  Hochstenbach LM, Zwakhalen SM, Courtens AM, van Kleef M, de Witte LP. Feasibility of a mobile and web-based intervention to support self-management in outpatients with cancer pain. Eur J Oncol Nurs. 2016;23:97-105

  Van den Heuvel LA, Spruit MA, Schols JM, Hoving C, Wouters EF, Janssen DJ. Barriers and facilitators to end-of-life communication in advanced chronic organ failure. Int J Palliat Nurs. 2016;22(5):222-9

  C.A. Verberkt, M.H.J. van den Beuken-van Everdingen, F.M.E. Franssen, C.D. Dirksen, J.M.G.A. Schols, E.F.M. Wouters, D.J.A. Janssen. A randomized controlled trial on the benefits and respiratory adverse effects of morphine on refractory dyspnea in patients with COPD: protocol of the MORDYC study. Contemporary Clinical Trials. 2016;47:228-34

  Marieke H.J. van den Beuken-van Everdingen, MD, PhD,  Laura M.J. Hochstenbach, MSc, Bert E.A.J. Joosten, PhD, Vivianne C.G. Tjan-Heijnen, MD, PhD, Daisy J.A. Janssen, MD, PhD. Update on prevalence of pain in patients with cancer: Systematic review and meta-analysis. J Pain Symptom Management. 2016;51(6):1070-90

  Marieke HJ van den Beuken-van Everdingen, MD, PhD, Alexander de Graeff, MD, PhD,Joost LM Jongen, MD, PhD,Denise  Dijkstra, MsC, Irina Mostovaya, MD, PhD, Kris C Vissers, MD, PhD, on behalf of the working group national guideline “Diagnosis and treatment of cancer pain”. Pharmacological treatment of pain in cancer patients: the role of adjuvant analgesics, a systematic review. Pain Practice. 2016

  Hendriks LE, Hermans BCM, van den Beuken-van Everdingen MHJ, Hochstenbag MM, Dingemans A-M. Effect of bisphosphonates, denosumab and radioisotopes on bone pain and quality of life in non-small cell lung cancer patients with bone metastases: a systematic review. Journal of Thoracic Oncology. 2016;11(2):155-73

  2015
  Wagemans AMA, van Schrojenstein Lantman-de Valk HMJ, Proot IM, Metsemakers J, Tuffrey-Wijne I, Curfs LMG. End-of-Life Decision-Making for People With Intellectual Disability From the Perspective of Nurses. Journal of Policy and Practice in Intellectual Disabilities. 2015;12(4):294-302

  G. (Art) Vreugdenhil en M.H.J. (Marieke) van den Beuken-van Everdingen. Starten en stoppen met palliatieve tumorbehandeling, Overwegingen in het kader van kwaliteit van leven en kosten. Nederlands Tijdschrift voor Geneeskunde. 2015;159:A8729

  Loes M.T. Hoogveld, Dennis C.J.J. Bergmans, Sergej de Vries, Huub van Proemeren, Marieke H.J. van den Beuken-van Everdingen, Jan G. Zijlstra, Walther N.K.A. van Mook IC-patiënten die thuis willen overlijden. Hoe kun je deze laatste wens vervullen? Nederlands Tijdschrift voor Geneeskunde. 2015;159: A8711:1-5 

  Daisy J.A. Janssen, Marieke H.J. van den Beuken-van Everdingen en Jos M.G.A. Schols Verrast door de ‘surprise question’ Nederlands Tijdschrift voor Geneeskunde. 2015;159(17):730-3

  Hochstenbach LMJ, Courtens AM, Zwakhalen SMG, Kleef van M, Witte de LP. Self-management support intervention to control cancer pain in the outpatient setting: a randomized controlled trial study protocol. BMC Cancer. 2015;416(15). doi:10.1186/s12885-015-1428-1 

  Magdelijns FJH, Beuken van den-Everdingen van MHJ, Courtens AM, Janssen DJA. Behandeling van doorbraakpijn bij kanker. Ned Tijdschr Geneeskd. 2015;159:A8121

  2014
  Wagemans AMA, Wijmen FCB. Advance care planning: Proactief medisch beleid bij mensen met een verstandelijke beperking.Ned Tijschr Geneeskd. 2014; 158:A8433

  Vermeulen J, Verwey R, Hochstenbach LMJ, Weegen van der S, Man YP, Witte de LP. Experiences of multidisciplinary development team members during user-centered design of telecare products and services: A qualitative study. Journal of Medical Internet Research. 2014;16(5):e124.

  Janssen DJA, McCormick JR. Palliative care and pulmonary rehabilitation. Clin Chest Med. 2014. doi:10.1016/j.ccm.2014.02.006

  Houben CH, Spruit MA, Groenen M., Wouters EFM, Janssen DJA. Efficacy of Advance Care Planning: A systematic review and meta-analysis. J Am Med Dir Assoc.  doi.org/10.1016/j.jamda.2014.01.008

  2013
  Houben CHM, Spruit MA, Wouters EFM, et al. A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol. BMJ Open. 2014;4:e004465. doi:10.1136/bmjopen-2013-00446

  Beuken van den-Everdingen van MHJ, Geurts JW, Patijn J. Prolonged QT interval by methadone: Relevance for daily practice? A prospective study in patients with cancer and noncancer pain. J Opioid Manag. 2013;9(4): 263-267